Ahmed Adebowale AdedejiIsmail Adesina Abdus-SalamAminah Adeola AdedejiLanre OmotayoIbrahim OreagbaKudirat Aderonke AdedejiBankole James AyodeleEinas Mohammed ElHabibi AdamOluremi Nurudeen OlaleyeErnest TamboDrissa Makan Toure2025-09-292025-09-292025-09-02https://doi.org/10.1007/s44337-025-00395-6https://dspace.ughe.org/handle/123456789/1025Public health pharmacology (PHP) is an emerging interdisciplinary field that integrates pharmacological principles with public health strategies to optimize therapeutic outcomes at the population level. This perspective examines its rationale, significance, and potential impact in addressing pressing healthcare challenges such as antimicrobial resistance (AMR), adverse drug reactions (ADRs), medication access disparities, and chronic disease management. Through a narrative review of existing literature and expert consultations, we explore PHP's distinct role in complementing allied disciplines while addressing systemic gaps in healthcare delivery. This perspective suggests that public health pharmacology could enhance population health and equity outcomes by addressing health disparities and global one health challenges, strengthening pharmacovigilance, and improving the quality and supply of medical products.journal-article