Xueying ZhangYosuke YamadaHiroyuki SagayamaPhilip N. AinslieEllen E. BlaakMaciej S. BuchowskiGraeme L. CloseJamie A. CooperSai Krupa DasLara R. DugasMichael GurvenAsmaa El HamdouchiSumei HuNoorjehan JoonasPeter KatzmarzykWilliam E. KrausRobert F. KushnerWilliam R. LeonardCorby K. MartinErwin P. MeijerMarian L. NeuhouserRobert M. OjiamboYannis P. PitsiladisGuy PlasquiRoss L. PrenticeSusan B. RacetteEric RavussinLeanne M. RedmanRebecca M. ReynoldsSusan B. RobertsLuis B. SardinhaAnaliza M. SilvaEric SticeSamuel S. UrlacherEdgar A. Van MilBrian M. WoodAlexia J. Murphy-AlfordCornelia LoechlAmy H. LukeJennifer RoodDale A. SchoellerKlaas R. WesterterpWilliam W. WongHerman PontzerJohn R. SpeakmanLene F. AndersenLiam J. AndersonLenore ArabIssad BaddouBedu AddoStephane BlancAlberto BonomiCarlijn V.C. BoutenPascal BovetStefan BranthNiels C. De BruinNancy F. ButteLisa H. ColbertStephan G. CampsAlice E. DutmanSimon D. EatonUlf EkelundSonja EntringerCara EbbelingSölve ElmståhlMikael FogelholmTerrence ForresterBarry W. FudgeTamara HarrisRik HeijligenbergAnnelies H. GorisCatherine HamblyMarije B. HoosHans U. JorgensenAnnemiek M. JoosenKitty P. KempenMisaka KimuraWatanee KriengsinyosEstelle V. LambertChristel L. LarssonNader LessanDavid S. LudwigMargaret McCloskeyAnine C. MedinGerwin A. MeijerEric MatsikoAlida Melse-BoonstraJames C. MorehenJames P. MortonTheresa A. NicklasDaphne L. PannemansKirsi H. PietiläinenRenaat M. PhilippaertsRoberto A. RabinovichJohn J. ReillyElisabet M. RothenbergAlbertine J. SchuitSabine SchulzAnders M. SjödinAmy SubarMinna TanskanenRicardo UauyGiulio ValentiLudo M. Van EttenRita Van den Berg-EmonsWim G. Van GemertErica J. Velthuis-te WierikWilhelmine W. Verboeket-van de VenneJeanine A. VerbuntJonathan C.K. WellsGeorge Wilson2025-02-172025-02-172022-08-1910.1016/j.isci.2022.104682https://dspace.ughe.org/handle/123456789/206Lower ambient temperature (Ta) requires greater energy expenditure to sustain body temperature. However, effects of Ta on human energetics may be buffered by environmental modification and behavioral compensation. We used the IAEA DLW database for adults in the USA (n = 3213) to determine the effect of Ta (-10 to +30°C) on TEE, basal (BEE) and activity energy expenditure (AEE) and physical activity level (PAL). There were no significant relationships (p > 0.05) between maximum, minimum and average Ta and TEE, BEE, AEE and PAL. After adjustment for fat-free mass, fat mass and age, statistically significant (p < 0.01) relationships between TEE, BEE and Ta emerged in females but the effect sizes were not biologically meaningful. Temperatures inside buildings are regulated at 18-25°C independent of latitude. Hence, adults in the US modify their environments to keep TEE constant across a wide range of external ambient temperatures. Keywords: Human Physiology; Human activity in medical context; Human metabolism.enHuman PhysiologyHuman metabolism.Body temperatureHuman energeticsjournal-article